Our company is the office of the USA必宜DeBEE in the great China. The必宜DeBEE is a worldwide supplier of high pressure homogenizing systems to the Pharmaceutical, Biotech, Chemical, Cosmetic and Food industries. We are dedicated to advancing the technology of homogenization. Our mission is to give our customers the tools to create new products faster and to produce them more economically than ever before. Our high pressure homogenizers produce unprecedented results delivering the smallest, most uniform and evenly distributed particles often in ONE pass.
(Mr.Liu劉先生 Mb:13699703666)
All必宜DeBEE systems come equipped with the following features:
· Highest process intensity in the industry to 45,000 PSI
· Unmatched processing goals and results in ONE pass
· Patented modular Homogenizing Cell for maximum processing flexibility
· Users control pressure, flow, temperature, cavitation, shear, impact and duration
· Proprietary pump design for the highest performance and reliability
· PLC control for easy operation, monitoring and data collection
· Standard Dual Feed port available for liquid and solid processing
· Sanitary design for easy cleaning and low maintenance
· Proven linear scale-up to production
· Available options and accessories for customized solutions
必宜DeBEE homogenizing systems are suitable for a broad range of applications:
(Mr.Liu劉先生 Mb:13699703666)
Nano-particle size reduction:
Most of today’s applications for nano-particles such as sunscreens, targeted and controlled release drug delivery systems, transparent coatings, contrast agents, ink, etc. - utilize nano-particles in a liquid vehicle. To produce products such as these our customers need nano-particles in stable liquid emulsions and dispersions.
Emulsions:
Emulsions are stable mixtures of oil and water, with one of them dispersed into the other in the form of fine droplets. There are "oil-in-water" emulsions, such as salad dressing and skin care creams, and "water-in-oil" emulsions, such as margarine and nutraceuticals. Surfactants are added to facilitate emulsion formation through the reduction of the interfacial tension, which reduces the pressure gradient required for drop breakup.
The following important factors affect the stability and efficacy of the emulsions:
Droplet Size – surface area per unit volume and droplet size distribution.
Narrow particle size distribution – most of the droplets at or below the target size and no "tails" on the distribution graph.
Dispersions:
Many applications, such as injectible medications and fuel cells require suspensions of nanoparticles in an aqueous medium. Benefits of having small particles include:
· Sterilization by filtration · Reduced toxicity
· Longer shelf life · Ingredient protection
· Increased efficacy · Controlled release
· Odor and flavor masking · Non-surfactant creams
· Improved aesthetics · Finer liposome
Cell Rupture:
Cell rupture or disruption, is where the cell envelope is physically broken, releasing all intercellular components into the surrounding medium.
The controllable high intensity of DeBEE systems ideal for cell rupture, which is accomplished by three different mechanisms:
· Impingement on entry to the nozzle area
· High liquid shear in the nozzle
· Sudden pressure drop upon discharge
· The combination causes the cells to explode.
Dual Feed for Abrasive and Viscous Materials:
Effortlessly process waxes, ceramics and metal powders!
Some materials are very hard to process by a nozzle based homogenizer:
· Very viscous materials, which tend to clog the nozzle
· Hot materials, which may affect non-metal seals
· Hard and abrasive materials, which could cause rapid wear of the nozzle
· Materials that must be fed in direct powder form
A key feature of DeBEE homogenizers is a unique Dual Feed feature, which makes use of high pressure for size reduction without passing abrasive materials through machine parts that are sensitive to wear. It enables metered amounts of the difficult material to be fed through a special port beyond the nozzle, there to be processed by the high speed jet coming through the nozzle, avoiding the above problems.
Dual Jet for grinding:
Grind ceramics, metal powders and hard pigments.
Replace your bead mill or colloid mill systems with a reproducible, in-line process.
Processing Polymers:
While there are many processes available to produce the final products from polymer pellets DeBEE Homogenizers are called for when in-line processing, greater stability, size reduction, nano or micro technologies are requirements.
Nano DB - a series of economical, electric laboratory systems
Micro DB - an economical, air operated laboratory system
Mini DB - an Electric/Hydraulic operated laboratory system
DB 2000 - a rugged Pilot Plant system
DB 2000P -a high volume system that scales up linearly from laboratory units
USA 必宜DeBEE China office*Guangzhou Koga Process高嘉公司
Mr.Liu劉先生 Mb:13699703666 Tel: 020-85428666
Email: koga2006@126.com
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